Bioassay Design,Development,& Support

Cell Based Assays

  • General Cytotox. assessment
  • Rat/Mouse primary hepatocyte Toxicity
  • Human primary hepatocyte Toxicity
  • Cell migration and Chemotoxis
  • Apoptosis assays
  • Cytochrome-C
  • Caspases assay
  • Mitochondrial membrane potential
  • Oxidative-phosphorylation and Glycolysis
  • Degranulation and Protease, Glycosidase and
         Histamine quantitation
  • Assays for Cytokine and growth factor
         release
  • And many more…

Cytochrome-P450 Enzyme (CYP)

  • Human recombinant 1A2, 3A4, 2C9, 2C19 and
         2D6
  • Competitive inhibition
  • Time-dependent inhibition
  • Fluorescent Assay

Signal Trnsduction

  • cAMP Determination
  • Nitric Oxide Assay
  • Nitric Oxide Synthase
  • Cytokine and growth factor release
  • Kinases activity and inhibitor profiling

Enzyme kinetics

  • kM, kI , Vmax Determination
  • Inhibitor profiling
  • Mechanistic studies

Protein Production

  • Cloning, Expression, Purification of proteins/peptides of your interest.

Knock-Out/Knock-in Cell line Generation

  • CRISPR Based Knock-Out
  • Validation of Knock-Out

Antibody Production

  • Polyclonal Antibody Production
  • Monoclonal Antibody Production